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Koret Berkeley Tel Aviv Initiative (KBTI) in Computational Biology COVID-19 seminars
July 7 @ 10:00 am - 11:00 am PDT
Webinar link: https://berkeley.zoom.us/j/
Koret Berkeley Tel Aviv Initiative (KBTI) in Computational Biology presents two seminars on studies of COVID-19 spread. This is a joint seminar series between University of California, Berkeley and Tel Aviv University.
10:05 am PT: Adi Stern, Principal Investigator
School of Molecular Cell Biology and Biotechnology George S. Wise Faculty of Life Sciences
Tel Aviv University
Full genome viral sequences inform patterns of SARS-CoV-2 spread into and within Israel
Full genome sequences are increasingly used to track the geographic spread and transmission dynamics of viral pathogens. Here, with a focus on Israel, we sequenced 212 SARS-CoV-2 sequences and use them to perform a comprehensive analysis to trace the origins and spread of the virus. We found that returning travelers from the U.S. contributed dramatically more to viral spread relative to their proportion in incoming infected travelers. Using phylodynamic analysis, we estimated that the basic reproduction number of the virus was initially around 2.5, dropping by more than two-thirds following the implementation of social distancing measures. We further found high levels of transmission heterogeneity in SARS-CoV-2 spread, with between 2-10% of infected individuals resulting in 80% of secondary infections. Overall, our findings demonstrate the effectiveness of social distancing measures for reducing viral spread.
10:30 am PT: Joseph Lewnard, Assistant Professor
School of Public Health and Center for Computational Biology
University of California, Berkeley
Transmission dynamics of COVID-19: observations from the United States and India
Recent experience in China, Europe, and the United States demonstrates the threat posed by COVID-19 to public health and healthcare systems in high-income settings. Little is known about the threat posed by COVID-19 in low-resource settings where populations encounter prevalent overcrowding and healthcare capacity is limited. I will review the epidemiology of severe COVID-19 within a cohort of 9 million individuals in California and Washington State receiving healthcare from Kaiser Permanente during the first epidemic wave. I will then present data from comprehensive surveillance and contact-tracing studies from two states in South India, highlighting differences from the experience of high-income settings.
Webinar link: https://berkeley.zoom.us/j/95769042863?pwd=OWx3NkxCM0N0ck1sSUU0V2NvME1wZz09
If you have any questions, please email Kristen Martins-Taylor.