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Since 2007, The Right Care Initiative’s goal has been to apply scientific evidence and outcomes improvement strategies to reduce patient morbidity and mortality through a collaborative focus on achieving quality goals where performance metrics indicate that evidence-based, life-saving practices are not fully deployed. Data from the Integrated Health Care Association, the National Committee For Quality Assurance, the federal Agency for Health Care Quality and Research, the Commonwealth Foundation, CMS, and the Centers for Disease Control indicate two trouble spots where evidence-based patient management and clinical quality improvement will significantly enhance and save lives while preventing disability: cardiovascular disease, with particular emphasis on hypertension and lipid control; and diabetes, focused on heart attack and stroke prevention.